EquiGlow™ MT-2

Molecular Formula

C₅₀H₆₉N₁₅O₉

Melanotan II is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). It is engineered to bind with high affinity to melanocortin receptors, particularly MC1R, which plays a central role in regulating melanin production in the skin.

Its cyclic structure increases biostability and receptor selectivity, making it more resistant to enzymatic degradation compared to naturally occurring peptides. This enhanced stability contributes to its prolonged activity in research settings.

Mechanism of Action

Melanotan II mimics endogenous melanocortins by activating melanocortin receptors:

• MC1R activation → stimulates eumelanin production (darker pigmentation)

• Secondary activity at MC3R / MC4R → associated with appetite modulation and libido signaling pathways

Key Research Benefits

(For research and informational purposes only)

• Enhanced Melanin Production
  Promotes increased eumelanin synthesis, which may support pigmentation responses without excessive UV exposure.

• Photoprotective Potential
  Increased melanin levels may provide a degree of natural UV protection by reducing oxidative DNA damage in skin cells.

• Skin Tone Modulation
  Investigated for its ability to even skin tone and support pigmentation in conditions involving hypopigmentation.

• Appetite & Metabolic Signaling
  Interaction with central melanocortin receptors has shown effects on satiety and energy balance pathways in preclinical models.

• Libido Pathway Activity
  Observed to influence sexual arousal pathways via MC4R signaling in neurological studies.